Household ingredient · Stain remover (enzyme)

Detergent enzymes

Proteins that break down stains (protease for protein, amylase for starch, lipase for fat). EU detergent labels must list them.

  • Expert review pending

Concern level

Low concern Level 1 of 4 How concern levels work

A minor or very limited concern, such as being an ultra-processing marker only. The concern level sets how many points detergent enzymes costs on a product’s receipt.

What the evidence says

  • Respiratory sensitizer (occupational)Strong evidence

    Inhaled enzyme dust can cause respiratory allergy, mainly a workplace risk; products keep airborne exposure very low. [1]

Evidence tiers say how sure the evidence is, separately from how much it matters. About evidence tiers.

Rules around the world

How regulators treat Detergent enzymes
WhereStatusDetailsDateSource
European Union Permitted Detergents must list enzymes whatever their concentration (Annex VII A). — [2]

“Banned” means explicitly prohibited or withdrawn after review; “not permitted” means never authorized there. We use each regulator’s own words.

Popular products that list detergent enzymes

6 of the 17,000 most-scanned products in the US with a GoodSwap page list detergent enzymes.

Names GoodSwap recognizes on labels (21)
  • enzyme
  • lipase
  • amylase
  • enzymes
  • protease
  • cellulase
  • mannanase
  • pectinase
  • subtilisin
  • subtilisins
  • enzyme blend
  • alpha amylase
  • lipase enzyme
  • pectate lyase
  • xyloglucanase
  • amylase enzyme
  • protease enzyme
  • detergent enzymes
  • enzyme preparation
  • proteolytic enzymes
  • protease and amylase

Sources

  1. Enzymes in cleaning products: an overview of toxicological properties and risk assessment/management

    Regulatory Toxicology and Pharmacology · October 2012 · Peer-reviewed

    “Exceptions are the ability of some proteases to produce irritating effects at high concentrations and more importantly, the intrinsic potential of these bacterial/fungal proteins to act as respiratory sensitizers.”

    doi.org

  2. Regulation (EC) No 648/2004 of the European Parliament and of the Council of 31 March 2004 on detergents

    European Union (Official Journal) · Mar 31, 2004 · Law

    “The following classes of constituent, if added, shall be listed irrespective of their concentration: - enzymes, - disinfectants, - optical brighteners, - perfumes.”

    eur-lex.europa.eu