Food additive · Antioxidant

BHT (butylated hydroxytoluene)

E-number
E321
CAS
128-37-0

A synthetic antioxidant used to keep fats in cereals, snacks and packaging from going rancid. The FDA began a safety reassessment in 2025.

  • Food additive
  • Preservative
  • Expert review pending

Concern level

Low concern Level 1 of 4 How concern levels work

A minor or very limited concern, such as being an ultra-processing marker only. The concern level sets how many points BHT (butylated hydroxytoluene) costs on a product’s receipt.

What the evidence says

  • Under regulatory reviewInfo

    The FDA requested data for a post-market assessment in 2026 (Docket FDA-2026-N-2526). IARC places BHT in Group 3; EFSA (2012) set an ADI of 0.25 mg/kg body weight. [1][2][3]

Evidence tiers say how sure the evidence is, separately from how much it matters. About evidence tiers.

Rules around the world

How regulators treat BHT (butylated hydroxytoluene)
WhereStatusDetailsDateSource
United States Under review Permitted with limits (21 CFR 172.115); FDA post-market assessment under way. — [4]
European Union Restricted Permitted (E 321) only in listed foods with maximum levels. — [5]
Canada Permitted On Health Canada's List of Permitted Preservatives, with limits. — [6]

“Banned” means explicitly prohibited or withdrawn after review; “not permitted” means never authorized there. We use each regulator’s own words.

Popular products that list BHT (butylated hydroxytoluene)

169 of the 17,000 most-scanned products in the US with a GoodSwap page list BHT (butylated hydroxytoluene). The 12 most scanned:

Diets and allergens

Vegan
Yes
Vegetarian
Yes
Gluten-free
Yes

For the ingredient in general. Always check the package: a product’s own labels win.

Names GoodSwap recognizes on labels (16)
  • bht
  • e321
  • antioxidant bht
  • antioxidant e321
  • preservative bht
  • bht for freshness
  • bht as a preservative
  • butylated hydroxytoluene
  • bht to maintain freshness
  • bht to preserve freshness
  • bht butylated hydroxytoluene
  • bht added to maintain freshness
  • bht added to preserve freshness
  • bht added to preserve product freshness
  • bht added to packaging to preserve freshness
  • bht added to packaging material to preserve freshness

Sources

  1. List of Select Chemicals in the Food Supply Under FDA Review

    U.S. Food and Drug Administration · Jul 29, 2026 · Regulator

    “The table below includes select food ingredients (including food and color additives), food contact substances, and contaminants under FDA review as of May 12, 2026 .”

    fda.gov

  2. Agents Classified by the IARC Monographs, Volumes 1–142 (List of Classifications)

    International Agency for Research on Cancer (WHO) · IARC

    monographs.iarc.who.int

  3. Scientific Opinion on the re-evaluation of butylated hydroxytoluene BHT (E 321) as a food additive

    European Food Safety Authority · Mar 7, 2012 · Agency assessment

    “Based on the NOAEL of 25 mg/kg bw/day and an uncertainty factor of 100, the Panel derived an ADI of 0.25 mg/kg bw/day.”

    doi.org

  4. 21 CFR 172.115 BHT

    Electronic Code of Federal Regulations (eCFR), U.S. Office of the Federal Register · Nov 22, 2016 · Law

    ecfr.gov

  5. Commission Regulation (EU) No 1129/2011 of 11 November 2011 amending Annex II to Regulation (EC) No 1333/2008 by establishing a Union list of food additives

    European Union (Official Journal) · Nov 11, 2011 · Law

    “E 127 Erythrosine 200 only cocktail cherries and candied cherries”

    eur-lex.europa.eu

  6. 11. List of Permitted Preservatives (Lists of Permitted Food Additives)

    Health Canada · Oct 20, 2025 · Regulator

    “B.2 Butylated Hydroxyanisole n/a (a) Active dry yeasts (a) Preservative (a) 1,000 ppm n/a”

    canada.ca