Food additive · Flavor enhancer

Monosodium glutamate (MSG)

E-number
E621
CAS
142-47-2

The sodium salt of glutamate, an amino acid found naturally in tomatoes, cheese and broth; it adds a savory (umami) taste.

  • Food additive
  • Flavor enhancer
  • Ultra-processing marker
  • Expert review pending

Concern level

Low concern Level 1 of 4 How concern levels work

A minor or very limited concern, such as being an ultra-processing marker only. The concern level sets how many points monosodium glutamate (MSG) costs on a product’s receipt.

What the evidence says

  • Low concernStrong evidence

    The FDA considers MSG generally recognized as safe; some sensitive people report mild, short-lived symptoms after 3 g or more without food. EFSA set a group ADI of 30 mg/kg body weight for glutamates. [1][2]

  • Marker of ultra-processingInfo

    An additive class typical of ultra-processed foods (NOVA group 4). [3]

Evidence tiers say how sure the evidence is, separately from how much it matters. About evidence tiers.

Rules around the world

How regulators treat Monosodium glutamate (MSG)
WhereStatusDetailsDateSource
United States Permitted Generally recognized as safe; must be listed as monosodium glutamate. — [1]
European Union Permitted Permitted (E 621); EFSA group ADI 30 mg/kg body weight per day. — [2]

“Banned” means explicitly prohibited or withdrawn after review; “not permitted” means never authorized there. We use each regulator’s own words.

Popular products that list monosodium glutamate (MSG)

414 of the 17,000 most-scanned products in the US with a GoodSwap page list monosodium glutamate (MSG). The 12 most scanned:

Diets and allergens

Vegan
Yes
Vegetarian
Yes
Gluten-free
Yes

For the ingredient in general. Always check the package: a product’s own labels win.

Names GoodSwap recognizes on labels (20)
  • msg
  • e621
  • glutamate
  • sodium glutamate
  • flavor enhancer msg
  • msg flavor enhancer
  • flavor enhancer e621
  • flavour enhancer msg
  • monosodium glutamate
  • flavour enhancer e621
  • glutamate monosodique
  • flavour enhancers e621
  • monosodium l glutamate
  • monosodium glutamate msg
  • flavor enhancer sodium glutamate
  • flavor enhancer monosodium glutamate
  • monosodium glutamate flavor enhancer
  • flavor enhancers monosodium glutamate
  • flavour enhancer monosodium glutamate
  • flavour enhancers monosodium glutamate

Sources

  1. Questions and Answers on Monosodium glutamate (MSG)

    U.S. Food and Drug Administration · Jul 17, 2026 · Regulator

    “FDA considers the addition of MSG to foods to be “generally recognized as safe” (GRAS).”

    fda.gov

  2. EFSA reviews safety of glutamates added to food

    European Food Safety Authority · Jul 12, 2017 · Agency assessment

    “EFSA re-assessed the safety of glutamates used as food additives and derived a group acceptable daily intake (ADI) of 30 mg/kg body weight per day for all six of these additives.”

    efsa.europa.eu

  3. Ultra-processed foods: what they are and how to identify them

    Public Health Nutrition · April 2019 · Peer-reviewed

    doi.org